Molecular Genetics of Genomic Imprinting
نویسندگان
چکیده
Keywords Androgenetic Embryo An embryo with two paternal genomes, and no maternal genome, produced by nuclear transplantation. Chromatin DNA packaged around nucleosomes. The degree of packaging differs between active (euchromatic) and inactive (heterochromatic) chromosomal regions.
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Genomic Imprinting in Bipolar Affective Disorder
With recent advances in molecular genetics, a new mechanism proposed for the inheritance of Bipolar Disorder is Genomic Imprinting or Parent of Origin Affect. In this study of 79 consecutive first episode manic patients, predominantly male, we failed to establish the phenomenon of imprinting. With other proposed non-Mendelian patterns of inheritance, it may be that bipolar disorder is genetical...
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